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Acta bioquímica clínica latinoamericana

versão impressa ISSN 0325-2957


CARIAS PICON, Diamela; GUTIERREZ MARTINEZ, Marlén; CIOCCIA RUZZO, Anna María  e  HEVIA OPAZO, Patricio. Utility of chicken and soybean protein in well-nourished or undernourished rats with lactose-induced diarrhea. Acta bioquím. clín. latinoam. [online]. 2011, vol.45, n.1, pp.95-108. ISSN 0325-2957.

In the nutritional treatment of diarrhea, good results have been obtained using liquid formulas with chicken meat together with cereals and/or starchy vegetables, prepared at home or at the clinic. In a previous study, formulas prepared with chicken meat or isolated soybean protein were tested in the treatment of infantile diarrhea. In order to determine if the results obtained in children could be reproduced in rats, the objective of the present study was to evaluate the effectiveness of the same diets in the nutritional treatment of well-nourished as well as undernourished rats with lactose induced diarrhea. The results showed that all the rats with diarrhea absorbed and retained less of the dietary nutrients and consequently, grew less than their counterparts without diarrhea. However, the absorption and retention measured in the nourished as well as in the undernourished rats were similar, indicating that a short period of malnutrition previous to the diarrhea episode, did not affect rats' absorption capacity. In addition, similarly to the results previously obtained in children, the rats with lactose induced diarrhea utilised equally well the dietary nutrients present in the chicken as well as in the soybean protein based diets. These results confirmed the value of isolated soybean protein in the nutritional treatment of diarrhea and showed that lactose induced diarrhea in rats is an appropriate model to study the nutritional consequences of diarrhea.

Palavras-chave : Diarrea; Rats; Lactose; Nutrient absorption; Malnutrition.

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