Abstract

MARRA, Carlos Alberto  and  TACCONI DE ALANIZ, María Josefa. Emerging biomarkers for different human pathologies. Acta bioquím. clín. latinoam. [online]. 2013, vol.47, n.2, pp.363-376. ISSN 0325-2957.

This review aimed to analyze the possible clinical utility of various oxidative-nitrosative stress biomarkers, mostly derived from lipid metabolism, as a tool to be implemented in the differential diagnosis, prognosis, risk assessment, or the evaluation of the therapeutical strategies for chronic illnesses of the degenerative type. The available information concerning the utility of the biomarkers on male infertility due to varicocele, neurodegenerative disease such as Alzheimer, Parkinson or vascular dementia, prostate, lung and breast cancer, professional sprayers exposed to agrochemicals or type 2 diabetes patients was discussed. The main conclusion is that many of these emerging biomarkers could be implemented in clinica /biochemical analyses of human samples due to the fact that they can be obtained from non-invasive or minimal-invasive procedures and are easily determined.

Keywords : Biomarkers; Lipids; Diabetes; Cancer; Pesticides; Oxidative stress; Varicocele.

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