Resumo

SANCHEZ NEGRETTE, Olga; MONTEROS, María Concepción; DAVIES, Carolina  e  ZAIDENBERG, Mario Oscar. Diagnosis of Trypanosoma cruzi infection in Primary Public Health Centers of Salta, Argentina. Acta bioquím. clín. latinoam. [online]. 2013, vol.47, n.4, pp.701-707. ISSN 0325-2957.

Chagas disease is caused by the hemoflagelate parasite Trypanosoma cruzi, and represents a main concern in public health. In Argentina, blood transfusion and organ donation are systematically controlled for T. cruzi infection, and vectorial transmission has dropped significantly. The aim of this project was to implement the use of the equipment for collecting capillary blood and conservation in glycerine (Serokit) in the nursery service of Primary Health Care Centers (PHCC) in the city of Salta, and to know the seroprevalence of T. cruzi infection in PHCC patients. To that aim, the serological pair HAI and ELISA was carried out in samples preserved in Serokit, followed by analysis of blood samples taken by venous punction to confirm the results. During a two-year period, 1647 patients that were assisted at 28 PCHC were analyzed, resulting in 1.7% (29/1647) seropositive samples. Positive Predictive Value was 93.5% and Negative Predictive Value was 99.8%. Every seropositive child was given Benznidazole treatment. It can be concluded that use of Serokit for taking and preserving samples to diagnose serologically T. cruzi infection is recommended in PHCC that lack their own biochemistry laboratory.

Palavras-chave : Primary health care; Chagas disease; Serology; Children; Trypanosoma cruzi; Prevention and control.

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