Abstract

ROJAS, Susan; QUERALES, Marvin; RODRIGUEZ, Marniet  and  RODRIGUEZ, Yaniret. Uric acid and cardiovascular risk in sendentary adults with regular physical activity. Acta bioquím. clín. latinoam. [online]. 2016, vol.50, n.3, pp.453-461. ISSN 0325-2957.

Uric acid (final product of purine metabolism) has been associated with cardiovascular disease, even if it was not considered an independent factor. This molecule has paradoxical actions since its increase contributes to plasma antioxidant capacity. Given that physical exercise contributes to a rise in the concentration of this marker, the aim of this study was to evaluate serum levels and their relation to cardiovascular risk factors in adults with regular physical activity and compared to sedentary individuals. A total of 94 individuals were evaluated, 51 of them being sedentary and 43 physically active, to which body mass index, waist circumference, uric acid, glucose, triglycerides and total and fractionated cholesterol were determined. No statistically significant differences in the levels of uric acid between the study groups were found and a low frequency of hyperuricemia (<20%) was observed. In both groups, uric acid was positively associated to body mass index and abdominal circumference, while in the sedentary group there was also an association regarding serum glucose and triglycerides. No differences in the frequency of anthropometric and biochemical alterations evaluated according to uric acid levels were observed. In conclusion, the levels of uric acid and their association with traditional cardiovascular risk factors are similar in both sedentary individuals and in those with regular physical activity, suggesting further studies involving other cardiometabolic markers.

Keywords : Uric acid; Cardiovascular risk factors; Regular physical activity; Sedentary.

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