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Acta bioquímica clínica latinoamericana

On-line version ISSN 1851-6114

Abstract

FRANCO, Micaela; GIL, Pamela; OTTAVIANI, Mariano Andrés  and  BELLONI, Juan Alberto. Evaluation of analytical limits of performance in the laboratory of HIGA O. Alende of Mar del Plata. Acta bioquím. clín. latinoam. [online]. 2017, vol.51, n.1, pp. 115-122. ISSN 1851-6114.

The analytical limits of performance (ALP) are part of the programme design of analytical quality control. The goals of this study were to determine imprecision (VC), systematic error (SE) and total error (TE) of 14 clinical chemistry analytes in the routine and emergency laboratory of HIGA O. Alende of Mar del Plata, to evaluate their analytical performance in accordance with biological variability, and compare the data obtained. A retrospective study was performed using the record of quality controls. The ALP were obtained from BV to get the quality specifications for VC, SE and TE. Regarding VC, 78% of the analytes meet the criteria in the routine laboratory and 64% in the emergency. Regarding TE, in the routine laboratory, 90% meet the TE criteria, and 75% in the emergency. It can be concluded that, although most of the evaluated analytes meet at least the minimum established criteria, the results highlight the need to improve the analytical performance. Detecting the types of errors in the laboratory process is the first step to establish procedural and analysis controls. These are solutions that will improve the analytical quality, one of the pillars to optimize patient safety.

Keywords : Analytical limits of performance; Analytical quality; Biological variability; Imprecision; Systematic error; Total error.

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