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Acta bioquímica clínica latinoamericana

Print version ISSN 0325-2957On-line version ISSN 1851-6114

Abstract

ACOSTA GARCIA, Edgar et al. Zinc, copper and vitamins C, E and A in a pubertal overweight and insulin-resistant population. Acta bioquím. clín. latinoam. [online]. 2017, vol.51, n.2, pp.203-212. ISSN 0325-2957.

Vitamins (Vit.) C, E and A, together with zinc (Zn++) and copper (Cu++) play an important role in the prevention of comorbidities associated with obesity. The objective of this work was to evaluate serum concentrations (Sc) of Vit. C, E and A, and those of Zn++ and Cu++ in a pubertal overweight (OW) and insulin-resistant (IR) population. The study was descriptive, correlational and cross-sectional. Variables were compared between the normalweight pubescent population, non-IR and those OW (IR or non-IR). Correlations between variables were assessed using Pearson and Spearman tests, the Student t test, Mann-Whitney U test, Kruskal-Wallis test and the statistical Z. OW and IR adolescents presented lower Zn++ than those OW non-IR, and the control group (p=0.010). Probably it is being IR what defines this decrease since the Zn++ was similar in the pubertal population with and without OW. In the OW and RI group of adolescents, there was a frequency of alterations in vit. E/CT (<2.25 mmol/mol) of 12.0%, compared to 4.8% and 8.0% in OW and non-IR and control adolescents, respectively (p=0.012) OW and IR adolescents showed a lower antioxidant protection and lower Zn++ than other groups evaluated.

Keywords : Antioxidant vitamins; Zinc; Cupper; Overweight; Insulin resistant; Adolescents.

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