Revista argentina de microbiología
versión On-line ISSN 1851-7617
CORSO, A. y ARGENTINEAN SIREVA WORKING GROUP et al. Prevalence of mef and ermB genes in invasive pediatric erythromycin-resistant Streptococcus pneumoniae isolates from Argentina. Rev. argent. microbiol. [online]. 2009, vol.41, n.1, pp. 29-33. ISSN 1851-7617.
During the period 1993-2001, a total of 1,499 pneumococci isolates were recovered through the Argentinean surveillance of Streptococcus pneumoniae causing invasive disease in children under 6 years of age, 3.5% of which were erythromycin resistant. Among the 50 erythromycin-resistant strains available, 58% (n=29) harbored mefA/E genes (15 mefA, 30%; and 14 mefE, 28%), 34% (n=17) ermB, and 6% (n=3) both mefA/E plus ermB genes, while one isolate was negative for all the acquired genes studied. The England14-9 (42%), Poland6B-20 (20%) and Spain9v-3 (16%) clones were responsible for the emergence of pneumococcal macrolide resistance in pediatric population from Argentina.
Palabras clave : Streptococcus pneumoniae; Macrolide; Argentina; Mef; erm.