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Revista argentina de microbiología

Print version ISSN 0325-7541On-line version ISSN 1851-7617


BONOFIGLIO, Laura et al. Susceptibility to β-lactams in β-hemolytic streptococci. Rev. argent. microbiol. [online]. 2018, vol.50, n.4, pp.431-435. ISSN 0325-7541.

Group A (GAS), B (GBS), c (GCS) and G (GGS) β-hemolytic streptococci are important human pathogens. They cause infections of different severity and frequency. Nowadays, after 70 years of use, penicillin is still universally active against GAS, GCS and GGS. However, therapeutic failures have been recorded in 2-28% of pharyngitis cases (median: 12%) attributable to different causes. By contrast, some GBS with reduced susceptibility to penicillin have been described, especially in Japan. In this group of bacteria, it is important to highlight that confirmation by reference methods is mandatory when decreased susceptibility to penicillin is suspected as well as checked for the detection of the mechanisms involved.

Keywords : Streptococcus agalactiae; Streptococcus pyogenes; Streptococcus dysgalactiae subsp. equisimilis; β-Lactams; Penicillin; Susceptibility.

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