Abstract

CRAIEM, D. et al. Cardiovascular engineering: modelization of ventricular-arterial interaction in systemic and pulmonary circulation. Lat. Am. appl. res. [online]. 2005, vol.35, n.2, pp.111-114. ISSN 0327-0793.

The heart pumps pressure and flow signals with relevant amount of frequency components cushioned along the arterial system. A pressure transfer function approach was designed to evaluate the Ventricular-Arterial Interaction. Two transfer functions were calculated relating ventricular to arterial pressure. A frequency response analysis followed the time-domain adaptation. Additionally, a viscoelastic model was proposed to characterize the arterial wall mechanical behavior, using the elastic (E) and viscous (h ) moduli. Six merino sheep were instrumented and anesthetized. Pressure measurements were registered in both ventricles, in aorta and in the pulmonary artery. Diameters (sonomicrometry) were measured in both arteries. The frequency transfer function asymptotic negative slope, describing the attenuation within the dynamic range, resulted 5 times greater in aorta (p<0.05), what presents the systemic as a more selective circuit than the pulmonary. E and h resulted higher (p<0.05) in aorta than in the pulmonary artery whereas E/h was similar. The viscoelastic results might indicate a similar segmental (unit-cell) response in both arteries. The enhanced cushioning ability of the left circuit with respect to the right, might be understood as a more selective vascular filtering system. This filtering performance might be related to the functional length of unit-cell responses along the systemic circulation.

Keywords : Aorta; Pulmonary Artery; Transfer Function; Viscoelasticity.

        · text in English     · English ( pdf )