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Latin American applied research

versão impressa ISSN 0327-0793

Resumo

BIA, D. et al. Differences in conduit and buffering function among arteries, venous grafts and synthetic prosthesis: Implicances in the development of intimal hyperplasia. Lat. Am. appl. res. [online]. 2006, vol.36, n.1, pp.29-36. ISSN 0327-0793.

Usually vascular surgeons consider the use of vein grafts as the materials of first choice for bypass or reconstruction of small arteries, while synthetic prosthesis (i.e. polytetrafluoroethylene, ePTFE) plays a secondary role in this matter. However, the causes for the superior performance of vein grafts respect ePTFE remain unclear. Our aim was to compare the conduit (CF) and buffering function (BF) of arteries, with those of vein grafts and ePTFE. In vitro pressure (Konigsberg) and diameter (Sonomicrometry) were measured in ovine arteries and veins, and ePTFE prosthesis, under isobaric and physiological pressures levels. From stress-strain relationship the Kelvin-Voigt time constant was calculated to quantify the BF. The CF was evaluated as 1/ZC, where ZC is the characteristic impedance. Vein graft CF and BF were more similar to native arteries than those of ePTFE prosthesis. Consequently, the higher performance of vein grafts could be related with their superior matching with arteries.

Palavras-chave : Vascular Prostheses; Conduit Function; Buffering Function; Intimal Hyperplasia.

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