Latin American applied research
versión impresa ISSN 0327-0793
A pharmaceutically active material diclofenac was intercalated into a layered double hydroxide by co-precipitation method, release studies suggest that the result diclofenac acid-pillared hydrotalcites (Dic-LDHs) have significant sustained release effect. The complex materials were characterrized using XRD, FTIR, DSC-TG, EA and ICP. The result show that the interlayer distance of the Dic-LDHs is expanded to 1.83nm and the thermal stability of material increases after the intercalation of diclofenac.
Palabras clave : Diclofenac Acid; Hydrotalcites; Release; Assembly.