Resumen

VILLALBA, María I et al. Riesgo de anomalías congénitas en grupos étnicos de Sudamérica. Rev Arg Antrop Biol [online]. 2015, vol.17, n.1, pp.19-27. ISSN 1514-7991.

The objective of this study was to estimate the risk of congenital anomalies according to the ethnicity of the newborn's parents. A sample of 20,940 newborns with 10 specific congenital anomalies was selected, together with a similar group of controls, and separated by ethnic group. The risks for the 10 isolated congenital anomalies were estimated by logistic regression methods, adjusting for Propensity Score using the Mantel-Haenszel test. The results of the present study showed that Latin Europeans have a high risk for spina bifida, syndactyly 2-3 of toes, and hypospadias; Jews for hypospadias; natives (Amerindian) for microtia, oral clefts, preaxial polydactyly and anal atresia; African descendants for postaxial polydactyly and hypospadias, and Arabs for spina bifida. In conclusion, in South America some ethnic groups have an increased risk for some congenital defects, which are not attributable to parental age, socioeconomic status or the number of pregnancies, suggesting that certain ethnic groups are more susceptible to specific birth defects.

Palabras clave : defectos congénitos; ancestros; epidemiología; etnia; birth defects; ancestry; epidemiology; ethnicity.

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