Abstract

MARTIARENA, B et al. Determination of parameters for the evaluation of Phosphorus/Calcium metabolism in adult normal dogs. InVet [online]. 2014, vol.16, n.2, pp.57-61. ISSN 1668-3498.

Diseases that facilitate alterations in the metabolism of calcium (Ca) and phosphorus (Pi) are diverse. Knowing and interpreting normal parameters is fundamental to making a diagnosis. In this study both minerals were evaluated in the blood and urine of 52 healthy adult dogs in three age ranges in years old (group A: from 1 to 5, group B: from 6 to 10, and group C: older than 10). Calcium levels exhibited no significant difference across age groups. A significant increase (p = 0.03) in phosphorus was found in group C in relation to the other two groups. Based on the elimination of both minerals through the urine, evaluated from the fractional excretion (DIP and DICa) and the relation Ca or Pi / Creatinine, a non-significant tendency of a lower elimination of Pi through urine was observed, according to DIP values of group C (p = 0.055). The values of DIP and DICa were correlated with the ones in Pi or Ca/Cr in urine (r = 0.9, p < 0.0001). These results allow us to infer that the mineral/Cr relation can be used when evaluating elimination by urine. The age range must be taken into account when interpreting results of phosphorus in blood and urine, since groups older than 10 years old have higher minimum and maximum threshold levels than the other two groups.

Keywords : Calcium; Fractional excretion; Phosphorus; Metabolism; Dog.

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