Resumen

MICHELOUD, J.F. et al. Intoxicación de equinos por Senecio pp en el noroeste argentino. Rev. vet. [online]. 2017, vol.28, n.2, pp.126-131. ISSN 1669-6840.

The toxicity of several species of genus Senecio is well known worldwide. In Argentina there have been cases in cattle but records are scarce. In this paper equine seneciosis is described in two rural areas of argentinean northwest. Clinical and pathological findings characterized by hepatic fibrosis, megalocytosis, cholestasis and biliary hyperplasia, were recorded. In sick animals it was observed weight loss, depression, and ataxia. In grassing areas Senecio rudbeckiaefolius, Senecio madagascariensis and Senecio hieronymi were identified. Pyrrolizidine alkaloids were identified by gas chromatography coupled to mass spectrometry. Presence of senecionine, integerrimine, usaramine, jacozine, jacobine, senecivernine, platyphylline and neoplatyphylline was recorded. The results confirm Senecio poisoning in horses in Argentina and reveal the first finding of pyrrolizidine alkaloids in three endemic species of Senecio for Northwest Argentina

Palabras clave : equine; intoxication; Senecio; pyrrolizidine alkaloids; hepatotoxicity.

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