Revista argentina de neurocirugía
versión On-line ISSN 1850-1532
VILLEGAS, Roberto A y CAMPUTARO, Luis A. Infección relacionada con el drenaje ventricular externo: Tratamiento intravenoso versus intratecal. Revision de la literatura. Rev. argent. neurocir. [online]. 2006, vol.20, n.3, pp. 133-136. ISSN 1850-1532.
Due to the emergency of external ventricular drainage infections, caused by multiresistant bacterial strains, and the need to treat them with antibiotics, whose action in the central nervous system is controversial, arises the therapeutic necessity to administer antibiotics whose benefits should be evaluated. We searched the Pubmed Library. The data were extracted from published studies between 1987-2005. In this revision the results were analyzed, comparing endovenous versus intrathecal treatment in patients with a ventriculostomy associated infection, the antibiotics that were used and their cerebrospinal fluid (CSF) levels according to each route. Finally, even though there is a lack of clear evidence, we proposed which patients could benefit with each treatment. We conclude that a randomized prospective study, comparing the benefits of each treatment is needed.
Palabras clave : Infections; Treatment; Ventriculitis.