Revista argentina de neurocirugía
versión On-line ISSN 1850-1532
RABADAN, Alejandra T. et al. Consenso para el tratamiento de las metástasis cerebrales. Rev. argent. neurocir. [online]. 2006, vol.20, n.4, pp. 179-193. ISSN 1850-1532.
The advances in oncological therapies has made brain metastases treatment a major factor influencing the survival time and the quality of life patients with cancer. Although there are numerous publications on the issue, there is no consensus about the best treatment strategy. This is probably due to population heterogeneity in terms of functional status, type of neoplasia, control of the systemic disease, and the number and localization of the lesions in the central nervous system. Our objective is to present general recommendations based on a rational analysis in order to guide the practical management of brain metastases. With this purpose, a multidisciplinary team composed by neurosurgeons, neurooncologists, neuropathologist, radiotherapist and neurologists were brought together to conduct a thorough search in english and spanish publications through PubMed (1980-2006). The starting period was set at the beginning of the use of magnetic resonance in medical practice. Reviews and original articles with n= or >20 were selected. Also, book chapters of renowned authors in the different consulted areas were included. The assessment of the literature, in addition to the experience of the authors allowed the development of the "Consensus for the Treatment of Brain Metastases". Finally, the authors expect that the present work will contribute to the multidisciplinary approach in the management of brain metastases with simple and practical recommendations, and probably stimulating future developments in this field.
Palabras clave : Cerebral metastasis; Chemotherapy; Radiotherapy; Surgery.