Abstract

GONZALEZ RAMOS, Javier et al. Metástasis intracraneales en la infancia. Rev. argent. neurocir. [online]. 2007, vol.21, n.3. ISSN 1850-1532.

Objective. to describe and analyze a series of pediatric patients who underwent surgery for intracranial metastasis at our department, specially considering the paucity of publications in the literature on the topic in this age group. Material and method. the study is a retrospective review of the clinical charts of patients with intracranial metastasis seen between 1988 and 2006. Inclusion and exclusion criteria were established for the different cases. Results. In this period, 1740 cns tumors were operated on, of which 12 cases were intracranial metastasis (0.7%.). mean age of the children was 11 years. six patients were male and 6 female. location of the primary tumor was: suprarenal in 4 cases, in the bone in 2, and in the bladder, kidney, testicle, hypopharynx, facial bone, and thigh in 1 case each. Four patients had multiple metastasis: 10 located in the cerebral hemispheres, 2 in the skull bone, and 2 at the epidural level. all patients presented with symptoms due to the brain metastases. total resection was achieved in 9 cases, subtotal resection in 1, and partial resection in 2. mortality rate was 50%, with a mean follow-up of 23 months. Conclusion. the incidence rate of brain metastasis in children is much lower than the published incidence rates in adults. the location of the primary tumor and histology found were also different. We consider surgery, when possible, a good therapeutic option within the multimodal treatment of metastases.

Keywords : Intracranial metastasis; Pediatrics; Surgery; Treatments.

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