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Revista argentina de neurocirugía

On-line version ISSN 1850-1532

Abstract

GONZALEZ RAMOS, Javier; CORTEZ, Cristian; SCHWINT, Oscar  and  ZUCCARO, Graciela. Uso de pericardio humano en neurocirugía. Rev. argent. neurocir. [online]. 2009, vol.23, n.3. ISSN 1850-1532.

Objective. To describe and to analyze a series of patients operated in our service by different pathologies, in which we used pericardium of alive donor for dural closure, stored at 80°C below cero in our hospital. Method. A retrospective analysis was designed to evaluate the medical records of 33 patients in which human pericardium were used, in a period of time between 2006 and 2008. Results. The age of the patients ranged from 1 month to 19 years old (average age: 6.6). 17 were male and 16 female. The surgeries in which we used, by different reasons, human pericardium for dural closure were: 7 posterior fossa tumors, 6 supratentorial tumors, 5 traumatic brain injury (intracranial hypertension), 3 Arnold-Chiari malformations, 3 spontaneous haematomas, 2 arterio-venous malformations, 2 lumbo-sacral lipomas, 2 encephaloceles, 1 surgery for epilepsy, 1 spinal cord tumor, and 1 brainstem tumor. The complications found were: 2 pseudomeningoceles and 1 CSF fistula. There were no systemic allergic reactions or local skin changes or infections. Follow up: 18.6 months. Conclusion. We considered that human pericardium is an excellent, effective and safe cranial and spinal dural substitute, presenting advantages such as: to be impermeable, easy to suture and to handle, providing hermetic sealing, low antigenicidad and not to induce reactions to strange body.

Keywords : Duraplasty; Dural substitute; Bank of human grafts; Pericardium.

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