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## Revista argentina de cardiología

*versión On-line* ISSN 1850-3748

#### Resumen

VOLBERG, Verónica I. et al. Efficacy of the Peak to Mean Pressure Decrease Ratio for the Assessment of Aortic Stenosis Severity.* Rev. argent. cardiol.* [online]. 2006, vol.74, n.3, pp. 123-128. ISSN 1850-3748.

The aim of the present study was to evaluate the statistical efficacy of peak to mean pressure decrease ratio (G_{MAX}/ G_{MED}) for the assessment of aortic stenosis severity. We studied the echocardiograms of 212 consecutive patients (mean age: 74 years; range: 19-98 years; 100 males [47%]) with an aortic area calculated by the continuity equation (AAo) of 2 cm^{2}. We considered severe aortic stenosis: a maximal aortic velocity (V_{MAX}) 4 m/s, a mean gradient (G_{MED}) 40 mmHg or an AAo of 1 cm^{2}. We also performed the analysis taking an AAo 0.75 cm^{2} as severe aortic stenosis. We conclude that: 1) G_{MAX}/ G_{MED} ratio is directly but weakly correlated; 2) There is a great overlap among G_{MAX}/ G_{MED} ratio values corresponding to patients with different aortic stenosis severity; 3) The sensitivity, specificity and accuracy of G_{MAX}/ G_{MED} ratio for the diagnosis of severe aortic stenosis are of average magnitude; 4) The positive and negative predictive values of G_{MAX}/ G_{MED} ratio are modest, in the studied population; 5) The analysis of likelihood ratios demonstrated that G_{MAX}/ G_{MED} ratio has only a small clinical impact for the diagnosis of severe aortic stenosis; 6) More studies are needed before accepting G_{MAX}/ G_{MED} ratio as a useful clinical parameter for the diagnosis of severe aortic stenosis. The G_{MAX}/ G_{MED} ratio could be a surrogate criterion for AAo when it is not possible to assess all the variables needed for its calculation.

**Palabras clave
:
**Aortic stenosis; Echocardiography; Doppler.