Resumo

ALBERTAL, Mariano et al. Comparative Study of Patients Implanted with Drug-eluting stents versus Conventional stents: Clinical Results and Indications. Rev. argent. cardiol. [online]. 2006, vol.74, n.6, pp.377-383. ISSN 1850-3748.

Background Randomized studies have shown the superiority of drug eluting stents (DES) compared to conventional stents (CS). In our country, the information available regarding implantation of DES is scarce. Objective To compare the clinical results obtained in patients implanted with a DES versus a CS in a tertiary center of Argentina. Material and methods All patients undergoing elective angioplasty from April 2003 until June 2005 were included, and divided in two groups: patients subjected to implant of one or more DES (group DES, n = 373) and patients subjected to the implant of a CS (group CS, n = 857). Results Basal characteristics were similar in both groups. The group with DES had a higher percentage of anterior descending artery lesions (50.6 versus 40.6%; p < 0.001) and intrastent restenosis lesions (16.6 versus 8.7%; p < 0.001), as well as a smaller vessel size (3.01 ± 0.57 versus 3.11 ± 0.57; p = 0.068) and a greater lesion length (20.6 ± 9.0 versus15.9± 7.8, p < 0.001) than the group with CS. As to implanted stents, their total length was greater (36.7 ± 18.1 versus 28.2 ± 17.7; p = 0.002) and their mean diameter was smaller in the DES group than in the CS group (3.09 ± 0.47 versus 3.17 ± 0.44; p = 0.007). At 30 days follow up, the rate of death, infarction and emergency revascularization was similar. At one year, in the DES group, the incidence of new revascularizations decreased (7.2% versus 11.7%; > 0.001), secondary to a reduction in the rate of coronary surgery (1.4% versus 5.8%; p = 0.045). Conclusion The assessment of DES implantation in a tertiary center of Argentina showed that it is safe and, compared to implantation of CS, led to a lower reintervention rate, mainly by reducing the rate of revascularization surgery.

Palavras-chave : Myocardial ischemia; Coronary restenosis; stent.