Revista argentina de cardiología
versión On-line ISSN 1850-3748
PEREZ, Susana G.; BERNASCONI, Alejandro; BALLARIN, José y BOVER, Jordi. Cardiovascular Disease in Patients with Chronic Renal Failure: the Cardiorenal Axis. Rev. argent. cardiol. [online]. 2008, vol.76, n.3, pp. 215-218. ISSN 1850-3748.
Chronic renal disease has been associated with an increase in cardiovascular morbidity and mortality. It is currently a very frequent disorder in which calcium and phosphate metabolism and myocardial hypertrophy play an outstanding role, and it constitutes an independent risk factor for cardiovascular disease. Previous clinical studies have demonstrated the consequences of the alteration in renal function on the increase of cardiovascular risk. Patients with moderate to severe renal chronic disease have an exponential increase in cardiovascular mortality, even before developing renal failure. The present study summarizes the information of basic research on the cardiorenal axis, and establishes the need of animal models to study the factors interrelated with this axis.
Palabras clave : Chronic Renal Failure; Cardiovascular Diseases; Chronic Renal Insufficiency.