Abstract

BELZITI, César et al. Heart Transplantation and Bone Marrow Transplantation in a Patient with AL Amyloidosis and Refractory Heart Failure. Rev. argent. cardiol. [online]. 2009, vol.77, n.4, pp.309-311. ISSN 1850-3748.

Primary amyloidosis is a systemic infiltrative disease that compromises the heart and represents an important cause of restrictive cardiomyopathy. We describe a 35-year old man with advanced heart failure secondary to an infiltrative cardiomyopathy with amyloid deposition. A plasma cell neoplasm was also diagnosed. The patient evolved with rapid progression of symptoms and deterioration of ventricular function, and did not tolerate the adequate therapy due to the hematological disease. For this reason, he underwent heart transplantation followed by autologous bone marrow transplantation; no complications were reported. This is the first case of heart transplantation followed by bone marrow transplantation reported in our country for the treatment of cardiac amyloidosis.

Keywords : Heart Transplantation; Bone Marrow Transplantation; Amyloidosis; Heart Failure.

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