Revista argentina de cardiología
On-line version ISSN 1850-3748
PAEZ, Olga B et al. Progression of White Coat Hypertension to Sustained Hypertension After 10 Year Follow-upProgression of White Coat Hypertension to Sustained Hypertension After 10 Year Follow-up. Rev. argent. cardiol. [online]. 2012, vol.80, n.3, pp. 217-221. ISSN 1850-3748.
Background The long-term outcome of white coat hypertension (WCH) is still controversial despite the broad information currently available. Objective To evaluate the cumulative incidence of sustained hypertension (SH) among patients with white coat hypertension compared to normotensive patients 10 years after being included in the study. Methods A total of 250 patients of both genders were prospectively included with the following office blood pressure (OBP) and 24- hour ambulatory blood pressure monitoring (ABPM) values: The patients were divided into two groups: 129 patients with WCH and 121 normotensive patients, and were evaluated after 10 years of follow-up. Glucose blood level, lipid profile and left ventricular mass index (LVMI) were measured. Results Age, gender, smoking habits and glucose blood level were similar at baseline among normotensive patients and patients with white coat hypertension. Yet, BMI, total cholesterol levels, lipid levels and LVMI were significantly greater in white-coat hypertensive patients. Sustained hypertension was developed by 48 patients with WCH and 21 normotensive patients. We found an independent association between WCH and SH at 10 years of follow-up OR: 2.5 (95% CI 1.2-4.2). Conclusion Progression to sustained hypertension was greater in patients with white coat hypertension compared to normotensive patients.
Keywords : White Coat Hypertension; Prognosis.