Abstract

MASSON, Walter M; SINIAWSKI, Daniel; SORROCHR, Patricia  and  SCORDO, Walter. Which should be the goals of apolipoprotein A1?: Analysis of a healthy population in Argentina. Rev. argent. cardiol. [online]. 2012, vol.80, n.4, pp.304-308. ISSN 1850-3748.

Which should be the goals of apolipoprotein A1? Analysis of a healthy population in Argentina Background Recent studies have demonstrated that apolipoprotein A1 (ApoA) is a better predictor of cardiovascular risk than HDLC. However, the definite goals of this new marker have not been clearly defined. Objective The objective of this study was to infer the goals of ApoA from a healthy population. Methods The distribution of ApoA and HDL-C in 304 blood donors was analyzed according to gender. ApoA goals were assumed using two strategies: 1) a simple linear regression model, and 2) percentile analyses. Results In the percentile analyses, ApoA levels of 126 and 147 mg/ dL corresponded to recommended goals for HDL-C in men and women, respectively. The linear regression model showed that 40 and 50 mg/dL HDL-C corresponded to 140 and 158 mg/dL ApoA in men and women, respectively. Conclusion The findings of this study suggest that previously postulated ApoA goals should be reviewed in both genders.

Keywords : Apolipoproteins; Lipids; Risk Factors.

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