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Revista argentina de cardiología
On-line version ISSN 1850-3748
Abstract
NAU, GERARDO et al. Multicenter Experience of Transcatheter Aortic Valve Implantation Stratified by Risk in Latin American Centers. Rev. argent. cardiol. [online]. 2020, vol.88, n.2, pp.104-109. ISSN 1850-3748. http://dx.doi.org/10.7775/rac.es.v88.i2.16440.
Introduction:
Transcatheter aortic valve implantation (TAVI) has been evaluated in different scenarios of the broad spectrum of patients with severe symptomatic aortic stenosis. The choice of treatment starts through a risk assessment guided by a multidisciplinary team.
Purpose:
The aim of this study was to analyze the population undergoing TAVI in Latin America according to their risk.
Methods:
From March 2009 to December 2018, consecutive TAVI procedures registered in the Latin American multicenter registry were included. The indication of TAVI was made in each case by a multidisciplinary team set up by each center. The population is stratified according to the surgical risk evaluated by the STS-PROM score. Three groups were defined, based on the established STS-PROM cut-off points: high risk (RA, higher 8%), intermediate risk (IR, between 4%-8%) and low risk (RB, lower 4%).
Results:
770 patients were included in the analysis, resulting 50,2% female, with a mean age of 81 y/o (IQR 75.6-85.7). 29.8% were included in the AR group (STS-PROM 11 (9.3-16.7), 44% at intermediate risk (STS-PROM 6 (4.8-6.71) and 26.1% at low risk (STS-PROM 2.7 (2-3.24). The proportion of low-risk patients has increased significantly over the period of inclusion (ptrend 0.011). Femoral access (95%), being percutaneous in 69% of patients. Self-expanding valves were implanted in 80%. 23% of the valves were repositionable without differences across the groups. There was no differences in 30-day mortality (RA 10.4%, IR 6.48%, RB 5.9%, p 0.154). Reduction in mortality were observed (RA 13, 7-4.1%, p0.001; RB 11.7-0%; p 0.0023) during the analyzed period.
Conclusions:
Risk stratification through surgical “scores” continues to represent a very useful guide, however the indication of TAVI in the real world incorporates other factors not contemplated in the classical score, which modifies our decisions in daily practice.
Keywords : Aortic Valve Stenosis /Therapy; Heart Valve Prosthesis Implantation; Risk Assessment.