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Revista argentina de cardiología
On-line version ISSN 1850-3748
Abstract
GOLDARACENA, FRANCISCO et al. Nocturnal Hypertension and Cardiovascular Events at a Buenos Aires City Hospital. Rev. argent. cardiol. [online]. 2022, vol.90, n.1, pp.43-49. Epub Mar 01, 2022. ISSN 1850-3748. http://dx.doi.org/10.7775/rac.v90.i1.20475.
Background:
Nocturnal Hypertension (NHT) has an impact on cardiovascular morbidity and mortality. Our aim was to evaluate the association between NHT and cardiovascular events.
Methods:
We carried out a retrospective cohort study including adults which had an ambulatory blood pressure monitoring test between March 2017 and July 2020 at a hospital in Buenos Aires City Argentina, with up to 36 months follow-up. Univariate and multivariate analyzes were performed to identify associated factors.
Results:
Four hundred and ninety four patients were included in the final analysis, 48% male, average age 58.9 years. Sixty two percent (n=308) presented NHT. A higher incidence of the cardiovascular composite endpoint was found in this group compared to those who did not present it, 10.4% vs 3.8% (p=0.013). In the final multivariate Cox regression analysis NHT was an independent predictor of cardiovascular events (HR=3.9; 95% CI 1.56-9.81; p=0.001), even independently of daytime HTN and the different circadian patterns of pressure.
Conclusions:
In this contemporary cohort from Buenos Aires, NHT was related to cardiovascular events incidence. Different measures should be taken to increase NHT awareness and diagnosis.
Keywords : Hypertension; Cardiovascular Disease; Blood Pressure Monitoring, Ambulatory.