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Revista argentina de dermatología
On-line version ISSN 1851-300X
Abstract
CARBO AMOROSO, E et al. Psoriasis And Metabolic Syndrome: Retrospective Study About 22 Clinical Cases. Rev. argent. dermatol. [online]. 2010, vol.91, n.1, pp.00-00. ISSN 1851-300X.
Psoriasis is a chronic, immune mediated disease, characterized by erythematous scamous lesions, often associated with articular involvement. A large body of evidence demonstrates an underlying systemic inflammatory process, which is pathogenic. A new pattern of response of Th17 lymphocytes has been proposed as the accompanying Th1 and a possible dysfunction of regulatory Tcells. In recent years, the association with other chronic inflammatory conditions such as Crohn's disease, COPD, metabolic syndrome, atherosclerosis and cardiovascular complications. The aim of our study was to assess the severity of psoriasis patients who fulfilled the office of Dermatology at the Cullen Hospital of Santa Fe - Argentina and to determine the prevalence of those with metabolic syndrome. To determine the extent / severity of disease was used PASI score and the diagnosis of metabolic syndrome using the ATPIII definition. The 36% of participants were included within the definition of the disease for meet three of the five criteria for its diagnosis. From the data, we suggest the screening of cardiovascular risk factors in psoriasis patients.
Keywords : Psoriasis; Metabolic syndrome; Insulin resistance.