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Revista argentina de dermatología

versión On-line ISSN 1851-300X


LEROUX, MB  y  LASHAK, CR. Primary focal hyperhidrosis associated to primary erythromelalgia. Rev. argent. dermatol. [online]. 2014, vol.95, n.1, pp.17-22. ISSN 1851-300X.

Female patient, aged 30 years-old, attending a medical consultation with hyperhidrosis associated with episodes of warmth and sweating since childhood, located in face, neck, upper thorax and extremities. These episodes are accompanied by heat, pain and reddening in hands and feet. The symptoms disappear to cold exposure. These symptoms altered sleep, daily activities and social life. A positive family history with similar clinical characteristics was obtained. Hematological and immunological studies, as well as upper limbs electromyography and ecodoppler are within normal parameters. Unspecific microvascular alterations were observed with finger-periungueal video capillaroscopy. A provoking test yielded positive results when rising temperature to 39°C in upper limbs. The patient symptoms are compatible with focal primary hyperhidrosis. Heat, reddening and pain in the upper and low extremities responding to cold exposure and the positive family history led us to diagnose erythromelalgia. The hyperhidrosis treatment consisted of a topical application of 20% hexhydrate aluminum chloride. For erythromelalgia treatment 528 mg magnesium citrate pills, 2-4 daily were administered. Literature review to find out association of primary focal hyperhidrosis with primary familiar erythromelalgia was negative.

Palabras clave : Erythromelalgia; Hyperhidrosis; Nailfold capilaroscopy; Magnesium citrate.

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