Abstract

CORTI, M et al. Subacute disseminated histoplasmosis in a patient with aids. Early oral lesions: A case report and review of the literature. Rev. argent. dermatol. [online]. 2014, vol.95, n.4, pp.12-20. ISSN 1851-300X.

Histoplasmosis is an endemic mycosis caused by a dimorphic fungus, Histoplasma capsulatum. Histoplasmosis is a fungal disease most prevalent in patients with advance HIV/AIDS disease and CD4 +T cell counts less than 100 cells/uL. Acute and subacute disseminated forms of the disease result from reactivation of latent infection and are much more severe in patients with AIDS compared with other immunodeficiencies. In some cases, oral lesions appear to be the only primary manifestation of the disease and may compromise the tongue, palate or the oral mucosa. Here we present a patient with infection by the human immunodeficiency virus (HIV) who developed a subacute disseminated histoplasmosis with ulcerative lesions in the oral mucosa as the initial manifestation of the opportunistic disease.

Keywords : Histoplasma capsulatum; Oral cavity ulcers; HIV-AIDS.