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Revista argentina de dermatología

versión On-line ISSN 1851-300X


PEREZ-ELIZONDO, AD. Erythema nodosum associated to a myeloproliferative process in a child. Rev. argent. dermatol. [online]. 2015, vol.96, n.1, pp.30-35. ISSN 1851-300X.

Erythema nodosum is a rare acute reactional inflammatory dermatoses, with a prevalence of two-three cases per 10.000 in habitants per year. It can occur at any age, appearing more in women (3-5:1) between 20 and 45 years; there seems to be a seasonal incidence during the first half of the year. It is an even rarer tegumentary pathology in children. There are few isolated cases and small groups of patients reported in the medical literature. Brilliantly described by Willan in 1798 and later supplemented by von Hebra in 1866, it is a septal panniculitis with interlobular septa of the subcutaneous fatty tissue involvement without vasculitis. An immune response to different antigens with deposit of immunoglobulins (IgM) and complement fractions (C3) in the deep perivenular plexus is hipothetized, probably involving a delayed hypersensitivity reaction. It has a benign nature and autolimited course; it resolves spontaneously within three to six weeks, sometimes with outbreaks of repetition for months or even years.  I present a case of a child of 9 years of age whose tegumentary lesions are associated an acute myeloblastic leukemia with fatal outcome.

Palabras clave : Paniculitis; Erytherma nodosum; Leukemia.

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