SciELO - Scientific Electronic Library Online

vol.96 número2Coexistencia de vitiligo y psoriasis, serie de casos y perspectivas etiopatogénicas índice de autoresíndice de materiabúsqueda de artículos
Home Pagelista alfabética de revistas  

Servicios Personalizados




  • No hay articulos citadosCitado por SciELO

Links relacionados

  • No hay articulos similaresSimilares en SciELO


Revista argentina de dermatología

versión On-line ISSN 1851-300X


HALAC, S et al. Hailey-Hailey disease: report of two cases. Rev. argent. dermatol. [online]. 2015, vol.96, n.2, pp.92-102. ISSN 1851-300X.

Hailey-Hailey disease is an autosomal dominant disorder characterized by acantholysis. It is caused by mutations of ATP2C1 gene encoding the secretory pathway Ca++/Mn++ ATPase localized in Golgi apparatus. It usually presents as erythematous, erosive plaques with fissures at folds and sites of friction. The course is chronic, with relapses and remissions. Treatment options are neither specific nor totally effective for this disease. Topical corticosteroids in combination with antibiotics, systemic, surgical and physical therapy can be used. We report a female patient with self-limited disorder and another one with extensive disease, poor adherence and little response to treatment.

Palabras clave : Hailey-Hailey disease; Familial benign chronic pemphigus; Acantholytic disorder.

        · resumen en Español     · texto en Español