Abstract

CAPELLO, Melina; SIMONSEN, Ulf  and  RUNGBY, Jørgen. Prevalence of hypertension and microalbuminuria in PCOS. Rev. argent. endocrinol. metab. [online]. 2010, vol.47, n.2, pp.40-52. ISSN 1851-3034.

The polycystic ovary syndrome (PCOS) is the most prevalent endocrinological disease in premenopausal women. The incidence is increasing, partly due to the increased incidence of obesity. PCOS is associated with an increased morbidity from cardiovascular disease and a number of risk factors described in the metabolic syndrome have been identified also in PCOS. We conducted a systematic review of the literature to descibe the prevalence of hypertension as a marker of permanent, and microalbuminuria as a marker of early, vascular stress. Hypertension was described as frequent among patients with PCOS, particularly frequent with obesity, severe menstrual disturbances and severe hyperandrogenemia. Microalbuminuria (MA) and premicroalbuminuria( PMA) as risk factors were poorly described in PCOS. However a prevalence of 16% or 24% (depending of the used criteria) of MA and a prevalence of 31,2% of PMA has been proposed among these patients, indicating a need to monitor, and in future trials intervene against, these risk factors.

Keywords : Hypertension; Microalbuminuria; Polycystic Ovary Syndrome.

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