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Revista argentina de endocrinología y metabolismo

On-line version ISSN 1851-3034


SABAN, Melina; SOUTELO, María Jimena  and  LUTFI, Julio Rubén. Metabolism of Carbohydrates in the Polycystic Ovary Syndrome. Rev. argent. endocrinol. metab. [online]. 2012, vol.49, n.2. ISSN 1851-3034.

Polycystic ovary syndrome (PCO) is a complex pathophysiological entity characterized by the presence of: menstrual irregularities, hirsutism, acne, obesity and insulin resistance. The estimated frequency of intolerance to carbohydrates and diabetes mellitus in patients with PCOS is 30-40 % and 5-10 %, respectively. In patients with PCO, the risk of developing type 2 diabetes mellitus is higher than in the general population. It should be noted that glucose intolerance is a major risk factor for developing diabetes and cardiovascular disease. The most sensitive test to detect glucose intolerance in women with PCO is the oral glucose tolerance test. Thus, the aim of this study was to analyze the different mechanisms involved in PCO and disorders of carbohydrate metabolism. No financial conflicts of interest exist.

Keywords : Polycystic ovary syndrome; Insulin resistance; Diabetes mellitus.

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