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Revista argentina de endocrinología y metabolismo

versión On-line ISSN 1851-3034


BELEN, L. et al. Glycaemic profile and its association with related factors insulin resistance in adult women without diabetes. Rev. argent. endocrinol. metab. [online]. 2018, vol.55, n.4, pp.31-40. ISSN 1851-3034.


The identification and intervention of the metabolic states prior to the diabetes mellitus type 2 (DM2), allows to avoid the appearance of the disease in a high percentage of the cases.


To determine the risk factors associated with the values of fasting altered glycemia (GAA) in non-diabetic adult women, concurrent to nutritional consultation at the Endocrinological Center of the Autonomous City of Buenos Aires (CABA), Argentina.

Materials and methods:

Cross-sectional and analytical study in a non-probabilistic sample of 316 women (40 to 65 years) without diabetes and not pregnant, who were classified according to fasting glycemia in two Groups (Gl <100 mg/dl and Gl≥100 and <126 mg/dl). They were studied as risk factors related to GAA: increased waist circumference (WC) >88 cm, unhealthy body mass index (BMI) ≥27 kg/m2, physical inactivity (less than 150 minutes a week), arterial hypertension (HT: ≥140/90 mmHg) and elevated TG/HDL-C ratio (≥3). The statistical program SPSS 19.0 was used to calculate mean, standard deviation and Chi square test. The level of statistical significance was set at p <0.05.


The mean age was 53.6 (SD = 6.5) years (35.8% premenopausal and 64.2% postmenopausal). 33.2% of the sample had GAA. 52.8% had unhealthy weight and 45.3% had increased BCA. 66.5% were sedentary, 21.5% had a diagnosis of hypertension and 22.2% had a high TG/HDL-C ratio. GAA was significantly associated with HTA (p<0,001) and elevated TG / HDL-C ratio (p <0,001).


The HTA values and the elevated TG/HDL-C ratio were the two factors that in this study were associated with GAA in this sample. Their research is recommended as early markers to prevent the risk of DM2.

Palabras clave : Altered fasting blood glucose; Prediabetes; Adult women.

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