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Acta toxicológica argentina

On-line version ISSN 1851-3743


RUBIO, Nélida Cristina; MARQUEZ, Cecilia  and  CONFALONIERI, Adriana. Validation of a fast screening method in urine by lC/MS/MS for compounds used in drug-facilitated crime (DFC) and its application to real samples. Acta toxicol. argent. [online]. 2016, vol.24, n.1, pp.21-32. ISSN 1851-3743.

The United Nations Office on Drugs and Crime (UNODC) in 2011, states that "The Drug-facilitated crime (DFC) is a general term that includes rape or other sexual assault, robbery, money extortion, as well as the deliberate maltreatment of the elderly or children under the influence of psychotropic substances". In this work we validated a qualitative and fast method from urine samples by LC/MS/MS for 39 compounds included in the Drug-facilitated crime lists. The aim was to reach a detection limit of 50% below the proposed concentration as "minimum required performance limits (MRPL)" by UNODC in order to be applied in real samples.

Keywords : Drug-facilitated crime; DFSA; LC/MS/MS; Validation.

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