Phyton (Buenos Aires)
versión ISSN 1851-5657
MANILAL, A et al. Antibacterial activity of Falkenbergia hillebrandii (Born) from the Indian coast against human pathogens. Phyton (B. Aires) [online]. 2009, vol.78, n.2, pp. 161-166. ISSN 1851-5657.
The antibacterial property of the red algae, Falkenbergia hillebrandii (Born) collected from the southwest coast of India (Indian Ocean) was evaluated against three multidrug resistant human pathogens. Four different solvents: ethyl acetate, dichloromethane, methanol and phosphate buffer saline (PBS) were used with this purpose. Dried samples extracted with methanol showed broadest and highest antimicrobial activity when compared to other solvents. However, PBS extract showed no antibacterial activity. The highly active compounds red alga, F. hillebrandii were fractionated and purified using different chromatographic systems, including reverse phase HPLC and GCMS. The analysis revealed that the most abundant metabolite was the oleic acid (51.33%) followed by n-hexadecanoic acid (42%).
Palabras llave : Antimicrobial activity; F. hillebrandii; Multidrug resistant human pathogens; Methanolic extract; Bioactive compounds.