Abstract

RIVERA, Luis Tomás et al. Características epidemiológicas de pacientes con tuberculosis en el Hospital Tránsito Cáceres de Allende. Rev. am. med. respir. [online]. 2014, vol.14, n.4, pp.404-411. ISSN 1852-236X.

Objectives: To determine the epidemiologic characteristics of patients diagnosed with TB who attended the hospital Transito Caceres de Allende of Cordoba, Argentina in the period from May 1st, 2010 to April 30th, 2013. Materials and methods: Descriptive, observational and prospective study in 106 patients older than 15 years old. Results: There was a higher frequency on the 15 to 35 years old (48%), male 55%, Argentine 90%, case fatality 4%, stable employment 50%, comorbidities: diabetes mellitus 19% , HIV 1%, tobacco smoking 61%, alcohol addiction 23%, consumption of illegal drugs 22%, BMI lower than 21: 63%. Bacteriologic diagnosis: positive direct smear microscopy 73%, positive culture 66% and pathologic histology 20%, treatment adherence: adherence 97%, healed 92 %, self administered treatment 96%, MDR-TB 3%. Forms of presentations: pulmonary TB 72%, extrapulmonary TB 28%. Radiological abnormalities: unilateral infiltrates with cavity 27%, unilateral without cavity 20%. Laboratory tests: Leukocytosis 15%, high erythrocyte sedimentation 82%, Adverse Drug Reactions: hepatoxicity 4%. Conclusions: Male young adult is more likely to become ill. Diabetes, HIV and BMI < 21 must prompt screening studies in symptomatic patients. Smoking habit, unemployment and bad social economics conditions are positive epidemiologic factors. Usual laboratory data is nonspecific but can provide some guiding. Thorax (chest) radiography, microscopy and culture are accessible diagnostic resources. MDR-TB is not yet a relevant problem in our hospital. Treatment related hepatotoxicity did not require interruption of therapy. Self administered treatment strategy with high adherence, low dropout and high healing rate indicate a big success of the program.

Keywords : Tuberculosis; Epidemiology; Treatment; Diagnostic methodology; Radiologic images.

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