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Revista americana de medicina respiratoria

On-line version ISSN 1852-236X


SANTAMARIA-ALZA, Yeison  and  SANCHEZ ROBAYO, Kelly Johana. Factores asociados con la presentación de afecciones respiratorias en pacientes con Artritis Reumatoide en una institución de Colombia entre el año 2012 y 2015. Rev. am. med. respir. [online]. 2016, vol.16, n.3, pp.206-213. ISSN 1852-236X.

Introduction: Rheumatoid arthritis affects 1% of the world population, and up to 73% of patients present respiratory disorders. In Colombia, there are no studies evaluating the relationship between the presence of pulmonary disorders and rheumatoid arthritis. Objective: To determine the factors associated with respiratory diseases in patients with rheumatoid arthritis. Methods: Case-control study (1:2) in 125 patients with rheumatoid arthritis. Descriptive, bivariate and multivariate analysis. Results: The mean age was 60.19 for cases and 53.15 years old for controls. 66.67% of cases and 86.75% of controls were female. The respiratory rate (RR), Disease Activity Score (DAS 28), smoking, exposure to biomass, dyspnea, weight loss and severe disease activity were higher in cases. The use of nonsteroidal antiinfammatory drugs (NSAIDs) and lefunomide predominated in controls. The bivariate analysis showed statistical significance with positive correlation between respiratory disorders and age, sex, smoking, exposure to biomass, dyspnea, weight loss, RR, DAS 28 and severe disease activity. There was a statistically significant negative correlation with lefunomide and NSAIDs. The multivariate analysis showed statistical significance in patients older than 65 years old, exposure to biomass, cough, dyspnea, severe activity and use of NSAIDs. Discussion: The results obtained are similar to those found in other studies. In addition, the presence of exposure to biomass appears as a variable strongly associated with the presentation of pulmonary disorders in patients with rheumatoid arthritis in our midst.

Keywords : Rheumatoid arthritis; Infection; Pulmonary diseases.

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