Abstract

LANZIERI¹, Pedro Gemal et al. Alcoholic cardiomyopathy aggravated by cancer chemotherapy. Insuf. card. [online]. 2013, vol.8, n.1, pp.41-45. ISSN 1852-3862.

Background. Cardiomyopathy (CMP) and heart failure (HF) are severe clinical conditions, both with high morbidity and mortality rates. The longer life expectancy of patients with cancer (CA) increases the risks of developing CMP and HF. Objectives. Report cases of alcoholic CMP aggravated by chemotherapy (CT) for Hodgkin's lymphoma. Case Report.Female, 50 years old, black with CMP alcoholic, was diagnosed with Hodgkin's lymphoma after screening of cervical adenomegaly. After eight months of CT with doxorubicin (530 mg/m2), bleomycin and vinblastine, showed worsening of functional class and frequent decompensation. There was a significant decrease in left ventricular ejection fraction, successive hospitalizations for decompensation and evolution to New York Heart Association (NYHA) functional class IV and stage D of the American Heart Association/American College of Cardiology. Conclusion. Theanthracyclinecardiotoxicityoccurs morefrequently inpatients with predisposing factors.Anypreviousinjuryto the myocardiumisrisk toCMP due to CT.In this case it is probable that the alcoholic CMP had clinical course aggravated by CT.

Keywords : Alcoholic cardiomyopathy; Alcoholism; Heart Failure; Chemotherapy; Doxorubicin; Hodgkin's lymphoma.

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