Abstract

THOMAS, Vanessa Bethina et al. Utilização da pressão positiva contínua nas vias aéreas na insuficiência cardíaca e apneia obstrutiva do sono: Revisão sistemática de ensaios clínicos. Insuf. card. [online]. 2019, vol.14, n.4, pp.135-140. ISSN 1852-3862.

Background. Heart failure (HF) and obstructive sleep apnea (OSA) patients have high morbidity and mortality rates, and treatment with continuous positive airway pressure (CPAP) may reduce these risks. Objective. Carry out a systematic review of randomized clinical trials on the effects of CPAP therapy in patients with HF and OSA. Sources of information. We searched the electronic databases PubMed, Embase, Web of Science and Lilacs in the last 10 years, without limits of language. Eligibility criteria. Randomized clinical trials, studies of patients with heart failure presenting reduced left ventricular ejection fraction (LVEF) (<50%) with OSA and who were treated with CPAP. Results. LVEF increased significantly in the groups that received CPAP therapy (baseline mean: 30.6%, post CPAP mean: 36.7%), as well as oxygen saturation (SaO2) (baseline mean: 94%; post CPAP mean: 95.3%) and there was a decrease in apnea/hypopnea index (baseline mean: 39.6; post CPAP mean: 12.3). Conclusion. Our systematic review of randomized clinical trials confirms that CPAP therapy in patients with HF and OSA improves predictors of morbidity and mortality.

Keywords : Heart failure; Obstructive sleep apnea syndrome; Continuous positive airway pressure.

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