SciELO - Scientific Electronic Library Online

vol.34 número1Avaliaçao da permeabilidade da dentina com erosao, após o uso de sistemas universais, autocondicionantes e convencionais índice de autoresíndice de assuntospesquisa de artigos
Home Pagelista alfabética de periódicos  

Serviços Personalizados




  • Não possue artigos citadosCitado por SciELO

Links relacionados

  • Não possue artigos similaresSimilares em SciELO


Acta Odontológica Latinoamericana

versão impressa ISSN 0326-4815versão On-line ISSN 1852-4834


PULITANO-MANISAGIAN, Gisela E  e  MANDALUNIS, Patricia M. Epithelial rests of Malassez in experimental animals at different ages. Acta odontol. latinoam. [online]. 2021, vol.34, n.1, pp.3-9.  Epub 01-Abr-2021. ISSN 0326-4815.

Epithelial rests of Malassez (ERMs) are fragments of Hertwig’s sheath in the periodontal ligament. There is extensive knowledge of their role in the etiology ofpathological processes and current evidence links them to maintenance of periodontal homeostasis. The aim of this study was to assess the behavior of ERMs with relation to the changes in periodontal tissues during growth in an experimental model with Wistar rats. Mesiodistal sections were made of the first lower molars from Wistar rats aged 1 month (n=7), 3 months (n=7) and 5 months (n=6). Sections were stained with H&E to evaluate number of ERMs/ mm, size/area of ERMs (μm2), height of periodontal ligament (PL.h) (pm), area of cement in the furcation zone (C.Ar) (μm2) and bone area related to the ERM zone (BAr/TAr)(%). Posthoc Bonferroni and ANOVA were applied for statistical analysis of results. Number of ERMs/mm declined significantly with age (1m: 4.34±1.51, 3m: 1.48±0.89, 5m: 0.27± 0.50, p<0.05), and there was great variability in size. There was significant increase in C.Ar (1m: 3418.96 ± 905.88, 3m: 19365.76 ± 5500.52, 5m: 32182.76 ± 7114.51, p< 0.05) and interradicular (BAr/TAr) (1m: 25.26 ± 2.37, 3m: 44.70 ± 3.95, 5m: 46.81 ± 7.80, p< 0.05: 1 vs 3, 1 vs 5). There was significant decline in PLh at 5 months (1m: 141.42 ± 29.25, 3m: 162.06 ± 28.21, 5m: 124.72 ± 18.67, p< 0.05: 1 vs. 3, 3 vs. 5). The decline in number of ERMs as animal age increases may be related to the significant increase in C.Ar and reduction in PL.h. It remains to ascertain its relationship with the increase observed in BAr/ TAr. Further studies are needed to learn more about the role of ERMs and their relationship with periodontal tissues when confronted with different normal and pathological stimuli.

Palavras-chave : epithelial rests of Malassez; periodontal ligament; alveolar bone; periodontium; histomorphometry.

        · resumo em Espanhol     · texto em Inglês     · Inglês ( pdf )