SciELO - Scientific Electronic Library Online

 
vol.30 issue139Choice of fruits for shakes and frequency of consumption: Preliminary results of a perception study toward healthy food products and consumption intentionKnowledge, interests and beliefs on food and nutrition in pregnant women author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

  • Have no cited articlesCited by SciELO

Related links

  • Have no similar articlesSimilars in SciELO

Share


Diaeta

On-line version ISSN 1852-7337

Abstract

DALTO, Paula  and  TAKEHARA, Natalia Andrea. Effect of probiotics on plasma cholesterol: Randomized controlled clinical trial. Diaeta [online]. 2012, vol.30, n.139. ISSN 1852-7337.

Objective: To determine whether the average drop in total cholesterol and LDL-cholesterol is higher in adult patients diagnosed with hypercholesterolemia who receive an hypocholesterolemic diet combined with a probiotic compared with those who receive only diet. Materials and methods: A randomized controlled clinical trial. The sample consisted of 46 patients of both sexes who attended the Piñero Hospital outpatient center with a diagnosis of hypercholesterolemia from August 2009 to April 2011. They were assigned to two groups: one received an hypocholesterolemic diet and another the same diet plus a dairy product containing probiotic Lactobacillus casei strain Shirota. Results: no significant differences were found in the average drop in total cholesterol between the group that followed the hypocholesterolemic diet and the one that followed the same diet combined with the probiotic (p = 0.386), whereas a significant difference (p <0.001) was observed between the initial and final total cholesterol in both. In the case of LDLcholesterol, no significant differences were found in its average drop between both groups (p = 0.313) as well, but there was a significant difference (p <0.001) between the initial and final LDL . Conclusions: in this study no significant differences were found in the average drop in total cholesterol and LDL-cholesterol between the group that followed only the hypocholesterolemic diet and the group that followed the diet with the probiotic. However, the results obtained confirm that the adoption of a meal plan designed to achieve a reduction in total cholesterol and LDL-cholesterol is effective, becoming a mainstay for the prevention and treatment of cardiovascular diseases.

Keywords : Total cholesterol; LDL-cholesterol; Hypocholesterolemic diet; Probiotics.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )

 

Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License