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Revista de la Asociación Argentina de Ortopedia y Traumatología

On-line version ISSN 1852-7434


SALCEDO ZUNINO, Leandro A et al. Valores de vitamina D en fracturas no consolidadas. Rev. Asoc. Argent. Ortop. Traumatol. [online]. 2016, vol.81, n.3, pp.163-169. ISSN 1852-7434.

Introduction: Absence of bone union after a fracture is generally multifactorial phenomenon. The objective of this study was to determine reference vitamin D values (25OHD3) in non-unions, and to study their association with age and localization. Methods: A prospective, observational and descriptive study was performed to evaluate 29 patients with non-union fractures. Serum vitamin D levels (25OHD3) were determined together with standard preoperative studies. Generalized models were used to estimate the effects of age and location, as well as to detect the group of patients with vitamin D levels lower than recommended. Results: The 68.9% had serum levels of vitamin-D lower than the normal value (30 ng/mL), which was inversely associated with age, being the age of 40 the cutoff point from which other characteristics, such as location, conditioned simultaneously the non-union. Conclusions: Most patients with a non-union fracture had vitamin D deficiency, and this phenomenon was more evident in patients >40 years. Prompt identification of patients with increased risk of presenting this deficiency is important, as treatment could reduce the incidence of fractures that evolve into a non-union.

Keywords : Vitamin D; Non-union; Pseudoarthrosis; Vitamin D deficiency.

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