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Revista de la Asociación Argentina de Ortopedia y Traumatología

On-line version ISSN 1852-7434


CARUSO, Juan Carlos  and  PATINO, Juan Martín. Osteopetrosis: Presentación de dos casos. Rev. Asoc. Argent. Ortop. Traumatol. [online]. 2019, vol.84, n.4, pp.386-392. ISSN 1852-7434.

Osteopetrosis, also known as Albers-Schönberg disease, is a disorder that is divided into four types and characterized by bone dysplasia and lack of bone resorption due to abnormal osteoclastic activity, resulting in the development of brittle and denser bone tissue that is prone to fractures that are difficult to treat surgically. On this paper, we discuss the cases of two patients with osteopetrosis and humeral shaft fractures, both of whom received conservative management. The objectives of our paper are to discuss our experience in the management of these cases and to review the available literature. Conservative management provides the best outcome for humeral shaft fractures in patients with osteopetrosis, given that bone quality in these patients excludes osteosynthesis. In addition, the use of implants may lead to complications such as infections, delayed fracture healing and pseudarthrosis, among others. Surgery should be reserved for certain patients, such as those with delayed fracture healing, pseudarthrosis, history of recurrent fractures, pre-existing fracture deformity, and those at risk of developing disabling deformities or that do not respond to conservative management.

Keywords : Osteoclasts; Humeral fracture; Osteopetrosis.

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