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Revista argentina de radiología
versión On-line ISSN 1852-9992
Resumen
FORLINO, Daniel et al. Craniofacial and skull base findings in Langerhans cell histiocytosis in pediatric patients. Rev. argent. radiol. [online]. 2013, vol.77, n.1, pp.39-48. ISSN 1852-9992.
Langerhans cell histiocytosis (CLH) is an uncommon entity, of unknown etiology, with an incidence of 2.6 at 5.4 per 1,000,000 children/year in the general population. It may have bone manifestations (solitary or multiple osteolytic lesions in flat, long and irregular bones) or multiorgan manifestations. We report the radiological findings in retrospective series of 17 pediatric patients aged 1 to 12 years old, with CLH in craniofacial and skull base. Radiological findings included osteolytic and soft tissue lesions occupying the orbit, sinuses, tympanic cavity and mastoid. In the mandible, reabsorption of the alveolar ridge with the appearance of floating teeth was observed. The anatomical complexity of the area studied required evaluation by CT and MRI with contrast. LCH disease should be considered in the differential diagnoses of craniofacial and skull base lesions, especially in pediatric patients.
Palabras clave : Histiocytosis; Pediatric; Craniofacial; Skull base.