Resumen

SERVENTE, Liliana; BIANCO, Corina; BENTANCOURT, Cecilia  y  ALONSO, Omar. ¹⁸ F-FDG PET/CT. Rev. argent. radiol. [online]. 2019, vol.83, n.1, pp.3-11. ISSN 1852-9992.  http://dx.doi.org/https://doi.org/10.1055/s-0039-1685234.

Purpose To determine the frequency and type of unexpected malignant/ premalignant tumor as a finding in ¹⁸ F-FDG PET/CT studies in oncological patients. Material and Methods Reports of ¹⁸ F-FDG PET/CT studies of oncological patients were reviewed retrospectively (from January 2014 to March 2017), with the finding of suspicious lesion of another malignant tumor. The information was obtained from certain "keywords" in the Center's database. The findings were confirmed by histopathology when possible and with clinical and paraclinical follow-up for at least six months. Results Of 4086 oncological patients, studied with ¹⁸ F-FDG PET/CT, a suspicious lesion of another malignant tumor was found in 130 (3.2%), 72 female and 58 male sex, average age 61 years. The most frequent primary tumors were: breast (n = 27), lung (n = 27) and colo-rectum (n = 20). 49 (1.2%) new malignant/premalignant tumors and two metastatic lesions were confirmed by histopathology. The location of the second primary tumor was: colon (n = 18), lung (n = 6), breast (n = 6), lymphoma (n = 3), ovary (n = 2), endometrium/cervix (n = 2), thyroid (n = 2) and others (n = 10). There were 28 false positive findings, 31 patients were not studied for progression and 20 patients were lost to follow-up. Discussion The prevalence of multiple malignant primary neoplasia (MMPN) is variable between 0.7 and 11.7%. In our series, a suspicious second tumor lesion was found in 130 cases (3.2%), of which 49 second tumors (1.2%) were confirmed, similar to that reported by other authors. Conclusions The detection rate of unsuspected malignant tumor was 1.2%, coincident with the literature. Any incidental finding suspicious of malignancy in ¹⁸ F-FDG PET/CT should be studied since in most cases it corresponds to early diagnosis with the possibility of curative treatment.

Palabras clave : synchronous neoplasm; incidental finding; ¹⁸ F-FDG; PET/CT.

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