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Revista argentina de radiología

versión On-line ISSN 1852-9992


MUNOZ, María Soledad; ROSSI, Carlos Enrique  y  MUNOZ, Marcelo. Radioactive Seed Localization for Nonpalpable Breast Lesions: Program Development & Implementation in Argentina. Rev. argent. radiol. [online]. 2019, vol.83, n.3, pp.102-112. ISSN 1852-9992.

Diagnostic intervention in breast disease started with preoperative localization of non- palpable lesions. Later, with the histological diagnosis obtained through biopsy techniques in mammography, ultrasound and magnetic resonance imaging, the localization of lesions has become a must. Traditionally, in Argentina, the localization technique was exclusively based on the insertion of harpoon-shaped guided wires and carbon suspension. Since 2001, the iodine-125 radioactive seed localization has emerged as a reliable and advantageous alternative for the patient, the surgeon and the hospital system, reducing scheduling conflicts between the breast imaging department and the surgical department, and allowing access to any quadrant with cosmetic incisions. The isotope provision is the key to satisfying the users demand, once they have known the merits of the procedure. The implementation of radioactive material for the localization of lesions has been tardy in all fields and in different countries, mainly due to justified regulations related to the acquisition of the isotope. As a result of joint efforts with the Autoridad Regulatoria Nuclear (Nuclear Regulatory Authority), the practice finally gained its deserved recognition in 2017. We conducted a review of the existing literature and described the technique and the logistics to obtain the approval of the sites that were interested in the deployment of a widely used procedure that has proved to be more advantageous than traditional methods.

Palabras clave : breast neoplasms/ diagnostic imaging; breast neoplasms /pathology; breast; neoplasms/surgery; radionuclide imaging/methods; ultrasonography/ methods.

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