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Revista Argentina de Salud Pública

Print version ISSN 1852-8724On-line version ISSN 1853-810X


KUHLMANN, Pamela Angelique et al. Implementation of a biosafety level 2 laboratory for molecular diagnosis of SARS-CoV-2 in Puerto Iguazú, Misiones. Rev. argent. salud pública [online]. 2022, vol.14, suppl.1, pp.54-54.  Epub Sep 05, 2022. ISSN 1852-8724.


The COVID-19 pandemic has created unprecedented challenges for laboratories around the world. National and subnational governments faced the urgent need to adapt institutions for the detection of SARS-CoV-2 in response to the health emergency declared in 2020. With the aim of increasing diagnostic capacity in the province of Misiones, a diagnostic laboratory of excellence was established within the “Instituto Misionero de Biodiversidad”. This article shares the steps taken and the challenges faced, in order to serve as a guide to other institutions.


The stages to establish the laboratory were: acquisition of equipment/reagents, adaptation/ renovation of the laboratory, incorporation and training of human resources, establishment of good practices and biosafety, selection of the extraction and detection methodology, implementation of quality controls and authorization.


Since its authorization, the “Laboratorio de Análisis Integral” has processed 1186 biological samples from suspected cases of COVID-19, becoming the second reference laboratory in Misiones.


The efficient articulation between the “Instituto Misionero de Biodiversidad” and the provincial Ministry of Health achieved the rapid implementation of this high complexity laboratory in a region of epidemiological importance.

Keywords : Molecular Diagnostic Techniques; Containment of Biohazards; SARS-CoV-2.

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