Abstract

BROSUT, H. Oscar et al. Surgical rescue of adrenal metastasis by melanoma following treatment with vemurafenib. Rev. argent. cir. [online]. 2018, vol.110, n.1, pp.1-12. ISSN 2250-639X.

We report the case of a patent presenting with a single melanoma metastasis in the adrenal gland, who underwent systemic treatment with vemurafenib (BRAF kinase inhibitor) in the frst instance and then underwent surgery. Current literature recommends surgical treatment of melanoma metastases and supports the use of inhibitors in patents with a BRAF kinase mutaton since they may improve disease control in a more sustained manner over tme. Although for many years surgery was the only therapy for stage IV disease, with modern drug therapies, the situaton has become more complex; this has created the challenge of determining the optmal combinaton and appropriate sequence of therapies; in this sense we consider it fundamental that cases such as the one presented here are discussed in tumor commitee meetings.

Keywords : metastaTCmelanoma, surgical treatment, BRAF, vemurafenib, adrenal metastasis..

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