Abstract

HOUSSAY, Solange et al. ¿Es el colesterol no-HDL un indicador de riesgo cardiovascular en las personas con diabetes mellitus?. Rev. Soc. Argent. Diabetes [online]. 2022, vol.56, suppl.1, pp.44-47. ISSN 0325-5247.

Type 2 diabetes (T2D) is a major cardiovascular risk factor (CVRF). Diabetes confers two to four times more cardiovascular risk (CVR). The risk is even higher in patients with T2D who have suffered an acute myocardial infarction (AMI) or cerebrovascular accident (CVA). The dyslipidemia of T2D consists of high fasting triglycerides, with greater postprandial excursion, low levels of HDLc and qualitative alterations of LDLc and HDLc. Appropriate glycemic control in T2D greatly improves lipoprotein abnormalities. Lipid-lowering therapy is key to reducing CVR in T2D. The CVR reduction achieved with statins is based on the reduction of LDLc. In patients who persist with an altered lipid profile despite highdose statins, the addition of other lipid-lowering agents to reduce atherogenic lipoproteins may be considered.

Keywords : non-HDL colesterol; statins; residual cardiovascular risk.

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